(Nasdaq: SPRC)

OUR NEW PROFILE IS:   (NASDAQ: SPRC)

CHECK OUT THE INVESTOR PRESENTATION HERE

SciSparc Ltd. Announces Initial Positive Results for the Cocaine Addiction Treatment of Clearmind Medicine Inc.

__________________________

Hello Everyone,

I hope that you were able to watch out last Nasdaq profile.  It exploded out of the gate and ran to highs of 19% from the opening trade.

We have another exciting Nasdaq company that we want you to pay attention to for today’s session.

Pull up SPRC immediately.

ABOUT SciSparc

SciSparc’s proprietary compounds capitalize on the biochemistry of receptors that specialize in modulating the central nervous system to create therapeutics that mitigate the adverse symptoms associated with CNS disorders.

Our primary platforms focus on the endocannabinoid system. The SciSparc pipeline composes both FDA – approved, and New Chemical Entities (NCEs) which we believe have strong potential to be indicated for targeted conditions, with no existing or sufficiently effective therapies.

Enhancing existing compounds with our proprietary technologies, we have developed novel therapies that demonstrate in clinical trials heightened bioavailability, significantly improved efficacy, lower dosage requirements, better safety profiles and a reduction in side effects.

CATALYSTS

  • Proprietary Technology with cutting-edge drug combinations addressing large global unmet medical needs
  • Two Phase 2 Assets addressing multi-billion markets and a Pending Phase 3* Clinical Trial
  • Attractive valuation & well capitalized to execute 2022 objectives
  • Key strategic partners, including leading universities, medical centers and KOLs
  • Preparing to file Investigational New Drug (IND) application in pain
  • Top-line pre-clinical SE study results in Status Epilepticus expected in the second half of 2022

2021- 2022 PRE-CLINICAL & CLINICAL ACHIEVEMENTS

  • SCI–110 for Alzheimer’s disease and Agitation – Recruited first patient for the Company’s Phase IIa
  • Entered an agreement with two clinical sites: Hannover Medical School in Hannover, Germany, and Tel- Aviv Sourasky Medical Center, in Tel-Aviv, Israel, to further the Company’s Phase IIb clinical study for SCI-110 for patients suffering from Tourette Syndrome
  • Entered into agreement with The Sheba Fund for Health Services and Research, to perform a pre- clinicalstudyforthe evaluationoftheCompany’sSCI-210drugdevelopmentprogram,forthe treatment of Status Epilepticus (SE)
  • Received positive top-line results for the Company’s proprietary compound, SCI-160, in a controlled pre-clinical trial on Neuropathic and Post-operative pain

ROBUST IP PORTFOLIO

Repurposing previously approved compounds qualifies SciSparc to take advantage of the FDA’s 505 (b)(2) application protocol. This potentially means lower risk, and an expedited development timeline. The result is a robust pipeline of product candidates well positioned to create significant shareholder value into the future.

SciSparc has built an intellectual property portfolio which currently comprises three granted U.S. patents and pending patent applications in six families, all focused on disorders of the central nervous system. Currently, our drug candidates are designed to treat Tourette Syndrome, Autism Spectrum Disorder, Epilepsy, Obstructive Sleep Apnea, Alzheimer’s Disease and Agitation, and Pain.

Our research and development efforts are focused on creating a proprietary and unique combination of products, some available already in the market (CannAmide™), products in the accelerated regulatory path of 505 (b)(2) application (SCI-110, SCI-210) and products that constitute a new chemical entity (SCI-160) in order to bring different products to market at different timelines and potentially enable us to generate immediate revenues for the company. augmenting FDA-approved natural and synthetic cannabinoids in combination with our proprietary compounds and technologies to create alternate therapies that potentiate the effects of cannabinoids and target the receptors implicated in modulating the central nervous system.

SCI-110, our proprietary drug candidate, containing Dronabinol (FDA approved synthetic form of THC), with the endocannabinoid palmitoylethanolamide (PEA).

Designed to stimulate cannabinoid receptors across the Central Nervous System and inhibit the metabolic degradation of endocannabinoids in order to improve uptake of THC, the expected benefits of SCI-110 are an increase in efficiency of oral administration, and in turn a decrease in dosage requirements, side effects and adverse events.

This product is being developed under the accelerated regulatory path of 505 (b)(2) application focused on augmenting FDA-approved natural and synthetic cannabinoids to create alternate therapies that potentiate the effects of cannabinoids and target the receptors implicated in modulating the central nervous system.

This approach qualifies us for access to the  FDA’s 505 (b)(2) regulatory strategy, created to facilitate the submission of novel drug candidates that meet specific criteria to the FDA for review. The 505 (b)(2) application provides us with several advantages as compared to a typical New Drug Application, including potential; lower risk and development costs, and a potentially expedited time to market. Indications currently being investigated for treatment with SCI-110 include:

– Tourette Syndrome- (TS) – Obstructive Sleep Apnea (OSA) – Alzheimer’s Disease and Agitation

NEWS

Tue Jun 7th, 2022

  • GlobeNewswire8:30 AM

    SciSparc Ltd. Announces Initial Positive Results for the Cocaine Addiction Treatment of Clearmind Medicine Inc.

Thu Jun 2nd, 2022

  • GlobeNewswire8:30 AM

    SciSparc Ltd. and Clearmind Medicine Inc. Collaboration Yields Another Patent Application for their Proprietary Psychedelic Combination to Treat Cocaine Addiction

Wed Jun 1st, 2022

  • GlobeNewswire4:07 PM

    SciSparc Ltd. Announces Closing of $10 Million Private Placement Priced At-the-Market

Tue May 31st, 2022

  • GlobeNewswire8:30 AM

    SciSparc to Collaborate with Polyrizon for Brain Targeting Using Intranasal Hydrogel Systems

Fri May 27th, 2022

  • GlobeNewswire9:15 AM

    SciSparc Announces Pricing of $10 Million Private Placement Priced At-the-Market

Thu May 26th, 2022

  • GlobeNewswire8:30 AM

    SciSparc Announces Ethics Committee Approval to Conduct a Phase IIb Trial in Tourette Syndrome

Tue May 24th, 2022

  • GlobeNewswire8:30 AM

    SciSparc and Clearmind Medicine Inc. Collaboration Yields Positive Results for its Psychedelic Combination Treatment

Tue May 10th, 2022

  • GlobeNewswire8:30 AM

    Clearmind Medicine Inc. and SciSparc Ltd., Collaboration Yields New Provisional Patent Application for Psychedelic Combination Treatment for Binge Behaviors

  • GlobeNewswire8:30 AM

    SciSparc Ltd. and Clearmind Medicine Inc. Collaboration Yields New Patent Application for Psychedelic Combination Treatment for Binge Behaviors

Mon May 2nd, 2022

  • GlobeNewswire8:41 AM

    SciSparc Files Annual Report for Year Ended December 31, 2021 and Provides Corporate Update

Thu Mar 31st, 2022

  • GlobeNewswire9:30 AM

    SciSparc Announces Closing of New JV Targeting Discovery of Potential Drugs for Cancers and Infectious Diseases

Wed Mar 30th, 2022

  • GlobeNewswire8:30 AM

    Prof. Avi Schroeder Joins SciSparc’s Scientific Advisory Board to Support the Company’s Development of SCI-160 for Treating Pain

Thu Mar 17th, 2022

  • PR Newswire8:00 AM

    SciSparc Announces Positive Results from Psychedelic-Based Pre-Clinical Trial

Thu Mar 10th, 2022

  • PR Newswire8:30 AM

    SciSparc Launches New JV Targeting Discovery of Potential Drugs for Cancers and Infectious Diseases

Tue Mar 8th, 2022

  • PR Newswire8:30 AM

    SciSparc Enters Collaboration for the Development of Innovative Psychedelic-Based Pharmaceuticals

Tue Feb 22nd, 2022

  • PR Newswire9:00 AM

    SciSparc to Present at Aegis Virtual Conference

Thu Jan 27th, 2022

  • PR Newswire8:30 AM

    SciSparc Presents New Leadership Lineup

Tue Jan 18th, 2022

  • PR Newswire8:02 AM

    SciSparc Advances Its Phase IIb Clinical Trial in Patients with Tourette Syndrome with its Proprietary Drug Candidate SCI-110

Tue Jan 11th, 2022

  • PR Newswire8:30 AM

    SciSparc Exploring Psychedelics as Possible Avenue to Expand Its IP Portfolio

Thu Jan 6th, 2022

  • PR Newswire9:00 AM

    SciSparc Announces Recruitment of First Patient for its Phase IIa Clinical Trial in Alzheimer’s Disease

Tue Jan 4th, 2022

  • PR Newswire8:44 AM

    SciSparc Issued U.S. Patent For Its Core Technology That Treats Central Nervous Systems Disorders

    ___________________________

TOP MANAGEMENT

Amitay Weiss

Chairman

Mr. Weiss has served as our Chief Executive Officer between August 2020 and January 2021and on our Board of Directors since August 2020. He is founder and Chief Executive Officer of Amitay Weiss Management Ltd. Prior to forming his company, he held several positions at Bank Poalei Agudat Israel Ltd., most recently as Vice President of Business Marketing & Development. He currently chairs and serves as director on the boards of several public companies. Mr. Weiss earned his B.A. in Economics from New England College, and his M.B.A. and LL.B from Ono Academic College in Israel – a branch of the University of Manchester.

Oz Adler, CPA

Chief Executive Officer and Chief Financial Officer

Mr. Adler joined the Company in September 2017, and since April 2018 serves as the Company Chief Financial Officer .Mr. Adler has a wide variety of managerial, financial, tax and accounting experience. Prior to joining the Company, Mr. Adler was employed as a CPA at Kost Forer Gabbay & Kasierer, a member of Ernst & Young Global. He currently chairs and serves as director on the boards of several private and public companies. Mr. Adler holds a B.A. in Accounting and Business Management from The College of Management, Israel.

Adi Zuloff-Shani,  PhD.

Chief Technologies Officer.

Dr. Zuloff-Shani joined the Company in February 2016, bringing more than 20 years of experience as a research and development executive in the bio-tech industry and launching start-ups in the healthcare industry. Dr. Zuloff-Shani brought 2 products from bench to market and is currently leading the development of several pharmaceutical products designated to the U.S., EU and Israeli markets.  Prior to joining us, Dr. Zuloff-Shani served as Vice President Development at Macrocure Ltd. (Nasdaq: MCUR) where she led all research and development activities. Dr. Zuloff-Shani earned her Ph.D. in Human Biology and Immunology from Bar-Ilan University, Israel.

Sincerely,

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